The evaluation of hemodialysis adequacy during the use of different dialysis membranes

Introduction: Hemodialysis efficacy that significantly influences morbidity and mortality of patients can be evaluated by different widely used indices of adequacy. Objective The aim of the study was to evaluate the adequacy of hemodialysis in the group of patients on maintenance hemodialysis and to examine the influence of different dialysis membranes on the indices of adequacy and frequency of symptoms and complications developing during dialysis treatment. Method The study involved 14 patients dialyzed in three successive months with three different types of dialyzers: E3 (Hemomed) - cuprophane membrane, 1.3 m2, F6 (Hemomed) - polysulfone membrane, 1.3 m2, CM23 (Zdravlje) - cuprophane membrane, 1.25 m2. Each type of dialyzers was used during one month, meaning during 12 successive 4-hour hemodialyses. Results Mean value of Kt/V index was 1.39±0.21 for E3 dialyzer, 1.18±0.24 for F6 dialyzer and 1.44±0.25 for CM23 dialyzer. The difference between the indices was statistically significant (p