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Influence of circadian clocks on adaptive immunity and vaccination responses

Authors :
Louise Madeleine Ince
Coline Barnoud
Lydia Kay Lutes
Robert Pick
Chen Wang
Flore Sinturel
Chien-Sin Chen
Alba de Juan
Jasmin Weber
Stephan J. Holtkamp
Sophia Martina Hergenhan
Jennifer Geddes-McAlister
Stefan Ebner
Paola Fontannaz
Benjamin Meyer
Maria Vono
Stéphane Jemelin
Charna Dibner
Claire-Anne Siegrist
Felix Meissner
Frederik Graw
Christoph Scheiermann
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Circadian rhythms have been shown to influence immune responses, but it is unclear whether this influences responses to vaccines. Here the authors show that dendritic cells migrate in a circadian rhythm meaning that interactions with T cells are altered leading to differential vaccine responses.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723 and 62447920
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4a62447920cd4f83a5fd19b48d8d06ab
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-35979-2