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Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus

Authors :
Yuanyuan Shi
Suihan Wu
Bo Yang
Baorong Yu
Yubo Yan
Jiayin Yang
Meng Chu
Xiaoyu Hu
Source :
Stem Cell Research, Vol 62, Iss , Pp 102801- (2022)
Publication Year :
2022
Publisher :
Elsevier, 2022.

Abstract

Human induced pluripotent stem cells (iPSC) resemble human embryonic stem cells with potential to differentiate into cells of all adult tissues. Nonetheless human iPSCs may have an epigenetic memory of their donor tissue origin, are easier to differentiate to those lineages, and their potential to other cell fates can be controlled. We generated a human iPSC line CIBi011-A from amniocytes of a healthy fetus. CIBi011-A serves as a useful source to investigate the epigenetic memory of iPSCs. As an iPSC line from a healthy donor, this line can also serve as a potential cell source from which to develop stem cell-based cell therapies.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
18735061
Volume :
62
Issue :
102801-
Database :
Directory of Open Access Journals
Journal :
Stem Cell Research
Publication Type :
Academic Journal
Accession number :
edsdoj.4c13d79b1d164db98d44dbcdcff6590d
Document Type :
article
Full Text :
https://doi.org/10.1016/j.scr.2022.102801