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Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- LATS1 is reported to regulate the transition of luminal-basal-like cell plasticity in breast cancer. Here the authors report that LATS1 limits the progression of luminal breast cancer by associating with NCOR1 nuclear corepressor to repress ERĪ±-downregulated genes in luminal cells.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.4ccbb8ac8c2f4c92a83690814f9d6056
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-34863-9