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Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus

Authors :
Aurélie Perrin
Anne-Sophie Gosselin-Grenet
Marie Rossignol
Carole Ginibre
Bethsabée Scheid
Christophe Lagneau
Fabrice Chandre
Thierry Baldet
Mylène Ogliastro
Jérémy Bouyer
Source :
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Abstract Urban Aedes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and Zika viruses. Insecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. Alternative control methods, such as the use of mosquito-specific entomopathogenic viruses should be explored. Numerous studies have focused on evaluating the potential of different densoviruses species as biological control agents. However, knowledge on the extent of inter- and intra-specific variations in the susceptibility of Aedes mosquitoes to infection by different densoviruses remains insufficient. In this study, we compared infection and mortality rates induced by the Aedes albopictus densovirus 2 in different strains of Aedes albopictus and Aedes aegypti mosquitoes. The two Aedes species were different in terms of susceptibility to viral infection. Under laboratory conditions, Aedes albopictus densovirus 2 appeared more virulent for the different strains of Aedes aegypti tested than for those of Aedes albopictus. In addition, we also found significant intra-specific variation in infection and mortality rates. Thus, although even if Aedes albopictus densoviruses could be powerful biocontrol agents used in the management of urban Aedes populations, our results also call into question the use of single viral isolate as biocontrol agents.

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
20452322
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.4cfa0373c86c4c09923ac6be8654d495
Document Type :
article
Full Text :
https://doi.org/10.1038/s41598-020-75765-4