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Genomic determinants of Furin cleavage in diverse European SARS-related bat coronaviruses

Authors :
Anna-Lena Sander
Andres Moreira-Soto
Stoian Yordanov
Ivan Toplak
Andrea Balboni
Ramón Seage Ameneiros
Victor Corman
Christian Drosten
Jan Felix Drexler
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Genomic analyses of spike glycoprotein genes of European bat SARS-related coronaviruses suggest that furin cleavage sites can be acquired in the bat reservoir via conserved molecular mechanisms, supporting a natural origin of SARS-CoV-2.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.4d9f53ac41784f55bbd79cfd2d322c2c
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03421-w