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Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain

Authors :
Chun Chieh Fan
Robert Loughnan
Carolina Makowski
Diliana Pecheva
Chi-Hua Chen
Donald J. Hagler
Wesley K. Thompson
Nadine Parker
Dennis van der Meer
Oleksandr Frei
Ole A. Andreassen
Anders M. Dale
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

How the tissue composition of the human brain is determined remains unclear. Here, the authors apply advanced analyses to two large imaging genetic datasets to identify and validate genetic loci that simultaneously influence multiple brain regions.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4e03d88fd08c40ea9a031f33f0f463ab
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30110-3