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Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability

Authors :
Michael B. Heskett
Athanasios E. Vouzas
Leslie G. Smith
Phillip A. Yates
Christopher Boniface
Eric E. Bouhassira
Paul T. Spellman
David M. Gilbert
Mathew J. Thayer
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Heskett et al. describe several members of a class of long non-coding RNAs, known as ASARs, which show distinct epigenetic regulation between subclonal lineages and are essential for normal DNA replication timing and stability of human autosomes.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4e4cb57c90794f0db665eeb98bc386ca
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-34099-7