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Pluripotency and differentiation of embryonic stem cells
- Source :
- E3S Web of Conferences, Vol 185, p 04034 (2020)
- Publication Year :
- 2020
- Publisher :
- EDP Sciences, 2020.
-
Abstract
- Mouse embryonic stem (ES) cells derive from the inner cell mass of an early embryo called blastocyst, making them promising resource for regenerative medicine. They possess two unique properties: self-renewal and pluripotency. Different ways can be used to assess which extracellular signal and factor inside ES cells has an impact on the pluripotency of ES cells. Nowadays, many extracellular signals and transcription factors have been identified, such as extracellular signals like LIF and transcription factors like Oct4. Studying the mechanism and function of these factors offers great insight and advance our understanding of pluripotency and self-renewal and thus shed light on regenerative medicine.
- Subjects :
- Environmental sciences
GE1-350
Subjects
Details
- Language :
- English, French
- ISSN :
- 22671242 and 20201850
- Volume :
- 185
- Database :
- Directory of Open Access Journals
- Journal :
- E3S Web of Conferences
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.4ed94326e1d44928829ee476629aed47
- Document Type :
- article
- Full Text :
- https://doi.org/10.1051/e3sconf/202018504034