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Pluripotency and differentiation of embryonic stem cells

Authors :
Liu Yinyin
Zhao Haibo
Liang Liang
Fan Peilei
Zhao Yujia
Feng Jinling
Zhang Ying
Gao Yang
Shen Zhengsheng
Source :
E3S Web of Conferences, Vol 185, p 04034 (2020)
Publication Year :
2020
Publisher :
EDP Sciences, 2020.

Abstract

Mouse embryonic stem (ES) cells derive from the inner cell mass of an early embryo called blastocyst, making them promising resource for regenerative medicine. They possess two unique properties: self-renewal and pluripotency. Different ways can be used to assess which extracellular signal and factor inside ES cells has an impact on the pluripotency of ES cells. Nowadays, many extracellular signals and transcription factors have been identified, such as extracellular signals like LIF and transcription factors like Oct4. Studying the mechanism and function of these factors offers great insight and advance our understanding of pluripotency and self-renewal and thus shed light on regenerative medicine.

Subjects

Subjects :
Environmental sciences
GE1-350

Details

Language :
English, French
ISSN :
22671242 and 20201850
Volume :
185
Database :
Directory of Open Access Journals
Journal :
E3S Web of Conferences
Publication Type :
Academic Journal
Accession number :
edsdoj.4ed94326e1d44928829ee476629aed47
Document Type :
article
Full Text :
https://doi.org/10.1051/e3sconf/202018504034