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Study on the Risk Factors of Preoperative Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

Authors :
Wenjie Chang MM
Bin Wang MM
Qiwei Li MM
Yongkui Zhang MD, PhD
Wenpeng Xie MD, PhD
Source :
Clinical and Applied Thrombosis/Hemostasis, Vol 27 (2021)
Publication Year :
2021
Publisher :
SAGE Publishing, 2021.

Abstract

Objective: The objective of this work is to discuss and analyze the related factors of lower extremity fracture complicated by preoperative deep vein thrombosis (DVT). Methods: A total of 11,891 patients with closed fractures of lower extremities were selected. By analyzing each patient’s gender, age, presence or absence of diabetes and hypertension, preoperative plasma D-dimer level, and color Doppler ultrasound of the lower extremity vein, the pertinent factors of the patients with lower extremity fractures complicated by preoperative DVT were analyzed. Results: A total of 578 with preoperative DVT were detected, displaying a total incidence of 4.86%. All patients were categorized into either the DVT group or non-DVT group. The results demonstrate that there were statistically significant differences between the 2 groups in age, the presence of diabetes and hypertension, the fracture site, and the preoperative plasma D-dimer level ( P < 0.05). Logistic multivariate analysis revealed that age, the presence of diabetes, and the preoperative plasma D-dimer level of patients were independent risk factors for lower extremity fracture complicated by DVT. Conclusion: Age, the presence of diabetes, the fracture site, and increased D-dimer levels were found to be potential risk factors and indicators for preoperative DVT in patients with lower extremity fractures. In addition, the preoperative plasma D-dimer level has certain guiding significance for the prediction of venous thrombosis after lower extremity fracture, which is conducive to the early prediction and diagnosis of DVT, but it often must be followed with good clinic acumen and examinations.

Details

Language :
English
ISSN :
19382723 and 10760296
Volume :
27
Database :
Directory of Open Access Journals
Journal :
Clinical and Applied Thrombosis/Hemostasis
Publication Type :
Academic Journal
Accession number :
edsdoj.4ff5585ec2c4ea8aa4c4ab18ff5ea71
Document Type :
article
Full Text :
https://doi.org/10.1177/10760296211002900