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Secreted midbody remnants are a class of extracellular vesicles molecularly distinct from exosomes and microparticles

Authors :
Alin Rai
David W. Greening
Rong Xu
Maoshan Chen
Wittaya Suwakulsiri
Richard J. Simpson
Source :
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Rai et al. characterise the properties of secreted midbody remnants, showing they are distinct from exosomes and microvesicles. The authors also find that these vesicles are engulfed by cells and promote anchorage independent growth and invasive phenotypes in NIH3T3 fibroblasts.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
4
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.513646f659d46ada6d3d94fad6062e7
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-021-01882-z