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scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Relationships between DNA methylation and transcription, and methylation and DNA accessibility can be probed but interrogating all three in the same single cells has not been possible. Here, the authors report the first single-cell method for parallel chromatin accessibility, DNA methylation and transcriptome profiling.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5160af085446eb92ec31544e77c471
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-03149-4