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Improvement of complex therapy of patients with pathology of scrotal organs formed by chronic brucellosis infection

Authors :
Glybochko Р. V.
Evdokimov A.M.
Liapina Е.Р.
Shuldiakov A. A.
Ponukalin A.N.
Blyumberg В.I.
Sedova L.N.
Source :
Саратовский научно-медицинский журнал, Vol 9, Iss 2, Pp 165-170 (2013)
Publication Year :
2013
Publisher :
Saratov State Medical University, 2013.

Abstract

The aim of the study is to improve the treatment of patients with male reproductive organs pathology, formed by chronic brucellosis infection. Material and methods: We have analyzed the dynamics of the clinical manifestations of diseases of the scrotal organs, data of physical and ultrasound studies, semen parameters, the quality of life in 22 patients with chronic brucellosis and the presence of orchitis / orchiepididymitis against conventional therapy (10 patients), and combined treatment with the inclusion of cycloferon (i/m, 2 injection rate from 5 (0.25g) with a break 10 days) — 12. Results: We have proved ability of cycloferon to reduce the severity of the inflammatory process in the testis and epididymis, with improving of spermatogenesis and the quality of life for patients. We have marked the reduction in the number of exacerbations of chronic orchitis / orchiepididymitis 2.4 times after the course of cycloferon, its good tolerability of patients, no side effects. Conclusion: Using these results, the presence of anti-inflammatory and immunomodulatory potencies, cycloferon can be recommended in treatment of inflammatory lesions of the scrotal organs in patients with chronic brucellosis.

Details

Language :
Russian
ISSN :
19950039 and 20762518
Volume :
9
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Саратовский научно-медицинский журнал
Publication Type :
Academic Journal
Accession number :
edsdoj.51bb20f96974023b1addb7a6864967e
Document Type :
article