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Model-Based Evaluation of Transmissibility and Intervention Measures for a COVID-19 Outbreak in Xiamen City, China

Authors :
Weikang Liu
Zhinan Guo
Buasiyamu Abudunaibi
Xue Ouyang
Demeng Wang
Tianlong Yang
Bin Deng
Jiefeng Huang
Benhua Zhao
Yanhua Su
Chenghao Su
Tianmu Chen
Source :
Frontiers in Public Health, Vol 10 (2022)
Publication Year :
2022
Publisher :
Frontiers Media S.A., 2022.

Abstract

BackgroundIn September 2021, there was an outbreak of coronavirus disease 2019 (COVID-19) in Xiamen, China. Various non-pharmacological interventions (NPIs) and pharmacological interventions (PIs) have been implemented to prevent and control the spread of the disease. This study aimed to evaluate the effectiveness of various interventions and to identify priorities for the implementation of prevention and control measures.MethodsThe data of patients with COVID-19 were collected from 8 to 30 September 2021. A Susceptible-Exposed-Infectious-Recovered (SEIR) dynamics model was developed to fit the data and simulate the effectiveness of interventions (medical treatment, isolation, social distancing, masking, and vaccination) under different scenarios. The effective reproductive number (Reff) was used to assess the transmissibility and transmission risk.ResultsA total of 236 cases of COVID-19 were reported in Xiamen. The epidemic curve was divided into three phases (Reff = 6.8, 1.5, and 0). Notably, the cumulative number of cases was reduced by 99.67% due to the preventive and control measures implemented by the local government. In the effective containment stage, the number of cases could be reduced to 115 by intensifying the implementation of interventions. The total number of cases (TN) could be reduced by 29.66–95.34% when patients voluntarily visit fever clinics. When only two or three of these measures are implemented, the simulated TN may be greater than the actual number. As four measures were taken simultaneously, the TN may be

Details

Language :
English
ISSN :
22962565
Volume :
10
Database :
Directory of Open Access Journals
Journal :
Frontiers in Public Health
Publication Type :
Academic Journal
Accession number :
edsdoj.51cfbbbe974db185117315b6b9fb14
Document Type :
article
Full Text :
https://doi.org/10.3389/fpubh.2022.887146