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Distinct kinetics of antibodies to 111 Plasmodium falciparum proteins identifies markers of recent malaria exposure

Authors :
Victor Yman
James Tuju
Michael T. White
Gathoni Kamuyu
Kennedy Mwai
Nelson Kibinge
Muhammad Asghar
Christopher Sundling
Klara Sondén
Linda Murungi
Daniel Kiboi
Rinter Kimathi
Timothy Chege
Emily Chepsat
Patience Kiyuka
Lydia Nyamako
Faith H. A. Osier
Anna Färnert
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Serological markers of recent Plasmodium falciparum infection could be useful to estimate incidence. Here, the authors identify a combination of five serological markers to detect exposure to infection within the previous three months with >80% sensitivity and specificity.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.52d616fbfd049d7ab986c391d76b171
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-27863-8