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A case report describing the immune response of an infant with congenital heart disease and severe COVID-19

Authors :
Danielle Wurzel
Melanie R. Neeland
Jeremy Anderson
Yara-Natalie Abo
Lien Anh Ha Do
Celeste M. Donato
Julie E. Bines
Zheng Quan Toh
Rachel A. Higgins
Sedi Jalali
Theresa Cole
Kanta Subbarao
Alissa McMinn
Kate Dohle
Gabrielle M. Haeusler
Sarah McNab
Annette Alafaci
Isabella Overmars
Vanessa Clifford
Lai-yang Lee
Andrew J. Daley
Jim Buttery
Penelope A. Bryant
David Burgner
Andrew Steer
Shidan Tosif
Igor E. Konstantinov
Trevor Duke
Paul V. Licciardi
Daniel G. Pellicci
Nigel W. Crawford
Source :
Communications Medicine, Vol 1, Iss 1, Pp 1-7 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Wurzel et al. describe the kinetics of the immune response in relation to clinical and virological features in a 5-month old infant with congenital heart disease and severe COVID-19. The immune response was characterised by an elevated inflammatory response in the acute phase of infection, followed by Th2 skewing and prolonged T cell activation.

Subjects

Subjects :
Medicine

Details

Language :
English
ISSN :
2730664X
Volume :
1
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.539146c00b4f4971b5652d9fc162ec20
Document Type :
article
Full Text :
https://doi.org/10.1038/s43856-021-00047-7