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In vitro vasodilatory effect of aqueous leaf extract of Thymus serrulatus on thoracic aorta of Guinea pigs

Authors :
Bekesho Geleta
Mebrahtu Eyasu
Selamu Kebamo
Asfaw Debella
Eyasu Makonnen
Abiy Abebe
Source :
Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 1, Pp 15-18 (2015)
Publication Year :
2015
Publisher :
Wolters Kluwer Medknow Publications, 2015.

Abstract

Objective: To investigate the vasodilatory effect of Thymus serrulatus (T. serrulatus) aqueous leaf extract on KCl (high K+, 80 mmol/L) induced precontracted isolated thoracic aorta rings on guinea pigs and the role of aorta endothelium on this action. Methods: Guinea pig thoracic aorta was removed and placed in an organ bath containing Krebs-Henseleit solution and aorta contractions were recorded isometrically. Results: The results revealed that T. serrulatus aqueous leaf extract (0.5-5 mg/mL) significantly (P

Details

Language :
English
ISSN :
22211691
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Asian Pacific Journal of Tropical Biomedicine
Publication Type :
Academic Journal
Accession number :
edsdoj.53e5dafd07214787bdcbcb745aed4193
Document Type :
article
Full Text :
https://doi.org/10.1016/S2221-1691(15)30164-7