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Hypolipidemic effect of ethanol extract from Chimonanthus nitens Oliv. leaves in hyperlipidemia rats via activation of the leptin/JAK2/STAT3 pathway

Authors :
Jianping Pan
Xilin Ouyang
Qi Jin
Wei Wang
Jiali Xie
Baoming Yu
Zhijie Ling
Qizhen Wu
Baoping Zheng
Source :
Molecular Medicine, Vol 28, Iss 1, Pp 1-12 (2022)
Publication Year :
2022
Publisher :
BMC, 2022.

Abstract

Highlights 1. COE improves lipid levels and lipase activities in hyperlipidemic rats. 2. COE ameliorates antioxidant enzyme activities and liver function in hyperlipidemic rats. 3. COE exerts a hypolipidemic effect by activating the leptin/JAK2/STAT3 pathway.

Details

Language :
English
ISSN :
10761551 and 15283658
Volume :
28
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Molecular Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.56c2e7274f0e44e98869160cb1c0190b
Document Type :
article
Full Text :
https://doi.org/10.1186/s10020-022-00589-z