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Effects of one-year supplementation with Phyllanthus niruri on fibrosis score and metabolic markers in patients with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial

Authors :
Muhammad Radzi Abu Hassan
Rosaida Hj Md Said
Zalwani Zainuddin
Haniza Omar
Siti Maisarah Md Ali
Siti Aishah Aris
Huan-Keat Chan
Source :
Heliyon, Vol 9, Iss 6, Pp e16652- (2023)
Publication Year :
2023
Publisher :
Elsevier, 2023.

Abstract

Background and purpose: and purpose: Non-alcoholic fatty liver disease (NAFLD) is a significant global health concern with limited pharmacotherapy options. This study aimed to evaluate the effectiveness of a standardized extract of Phyllanthus niruri in mild-to-moderate NAFLD. Materials and methods: This was a 12-month randomized controlled trial, in which adults with a controlled attenuation parameter (CAP) score >250 dB/m and a fibrosis score

Details

Language :
English
ISSN :
24058440
Volume :
9
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Heliyon
Publication Type :
Academic Journal
Accession number :
edsdoj.57ab0b059bf4605b35f514f20dc9845
Document Type :
article
Full Text :
https://doi.org/10.1016/j.heliyon.2023.e16652