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Treatment Outcomes and the Safety of Chemoradiotherapy With High-Dose CDDP for Elderly Patients With Head and Neck Squamous Cell Carcinoma: A Propensity Score Matching Study

Authors :
Jo Omata
Yushi Ueki
Takeshi Takahashi
Ryusuke Shodo
Keisuke Yamazaki
Kohei Saijo
Hisayuki Ota
Takafumi Togashi
Yuichiro Sato
Arata Horii
Source :
Frontiers in Surgery, Vol 8 (2021)
Publication Year :
2021
Publisher :
Frontiers Media S.A., 2021.

Abstract

Objective: We aimed to compare the outcomes and safety of chemoradiotherapy (CRT) between elderly and non-elderly patients with head and neck squamous cell carcinoma (HNSCC). It is difficult to assess the causal effect of age because of possible differences in general conditions among individuals. Therefore, we adjusted the background factors of elderly and non-elderly patients using propensity score matching (PSM).Methods: A total of 146 patients with HNSCC who received CRT were divided into an elderly (≥70 years, n = 35) and non-elderly group (

Details

Language :
English
ISSN :
2296875X
Volume :
8
Database :
Directory of Open Access Journals
Journal :
Frontiers in Surgery
Publication Type :
Academic Journal
Accession number :
edsdoj.59e069f2818b4775b888d6440c6677c7
Document Type :
article
Full Text :
https://doi.org/10.3389/fsurg.2021.753049