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Acute effects of synthetic cannabinoids on ventricular repolarization parameters
- Source :
- Türk Kardiyoloji Derneği Arşivi, Vol 47, Iss 5, Pp 384-390 (2019)
- Publication Year :
- 2019
- Publisher :
- KARE Publishing, 2019.
-
Abstract
- Objective: An association between ventricular repolarization parameters (VRPs) and ventricular arrhythmias has been demonstrated in previous studies. However, there are limited data related to a relationship between synthetic cannabinoids (SCs) and VRPs. The aim of this study was to analyze the acute effects of SCs on VRPs using electrocardiogram (ECG) measurements of the T-peak to T-end interval (Tp-e), Tp-e/QT ratio, and Tp-e/corrected QT (QTc) ratio. Methods: The present study included 58 patients who were admitted to the emergency department who used SCs (SC +) between 2014 and 2016, and 50 healthy control subjects (SC -). The QT and QTc intervals, Tp-e interval, Tp-e/QT, and Tp-e/QTc ratios were measured from a 12-lead ECG. These parameters were compared between groups and correlation analysis was performed. Results: The Tp-e and QTc intervals were significantly higher in SC + patients when compared with the SC- group (92.2+-10.0, 77.4 +-9.3, p
Details
- Language :
- English, Turkish
- ISSN :
- 10165169
- Volume :
- 47
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- Türk Kardiyoloji Derneği Arşivi
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5a345a9f660e40b599edbc7b718465ae
- Document Type :
- article
- Full Text :
- https://doi.org/10.5543/tkda.2019.64569