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Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities

Authors :
Jin-Hui Wang
Xiao-Dong Li
Shuai-Tao Kang
Guo-Yu Li
Xian Li
Source :
Molecules, Vol 16, Iss 5, Pp 3580-3596 (2011)
Publication Year :
2011
Publisher :
MDPI AG, 2011.

Abstract

In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities.

Details

Language :
English
ISSN :
14203049
Volume :
16
Issue :
5
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.5a8f89a9ad2446aabf71c068aa9785c3
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules16053580