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Research Progress on Mechanism and Intervention of Renal Function Injury in Hyperlipidemia Animal Model
- Source :
- Shiyan dongwu yu bijiao yixue, Vol 42, Iss 3, Pp 213-219 (2022)
- Publication Year :
- 2022
- Publisher :
- Editorial Office of Laboratory Animal and Comparative Medicine, 2022.
-
Abstract
- Hyperlipidemia is closely related to renal function damage, and they influence each other. Lipid deposition in the kidney affects the function and structure of glomerulus and renal tubules directly and indirectly, resulting in renal function injury. On the contrary, renal function damage further affects lipid metabolism and aggravates the progress of hyperlipidemia. At present, besides synthetic drugs, there are many non-synthetic drugs which have been well verified in the intervention of kidney injury in hyperlipidemia animal model. In this paper, the research progress in the mechanism of renal function damage and the related intervention using hyperlipidemia animal model at home and abroad in recent years were summarized.
- Subjects :
- hyperlipidemia
kidney injury
animal model
Medicine
Subjects
Details
- Language :
- Chinese
- ISSN :
- 16745817
- Volume :
- 42
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Shiyan dongwu yu bijiao yixue
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5c4d678f335445faaaf93800e3a2176e
- Document Type :
- article
- Full Text :
- https://doi.org/10.12300/j.issn.1674-5817.2021.116