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Rapid protein assignments and structures from raw NMR spectra with the deep learning technique ARTINA

Authors :
Piotr Klukowski
Roland Riek
Peter Güntert
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

The analysis of protein NMR spectra is time-consuming and can occupy a human expert for weeks or months. The researchers in this work present a deep learning-based method that delivers signal positions, chemical shift assignments, and structures of proteins within hours after completion of the NMR measurements.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.5c71525a53e84fd580eb761d30340173
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-33879-5