Back to Search Start Over

Induced pluripotent stem cells for cardiovascular therapeutics: Progress and perspectives

Authors :
I. V. Kizub
Source :
Regulatory Mechanisms in Biosystems, Vol 14, Iss 3, Pp 451-468 (2023)
Publication Year :
2023
Publisher :
Oles Honchar Dnipro National University, 2023.

Abstract

The discovery of methods for reprogramming adult somatic cells into induced pluripotent stem cells (iPSCs) opens up prospects of developing personalized cell-based therapy options for a variety of human diseases as well as disease modeling and new drug discovery. Like embryonic stem cells, iPSCs can give rise to various cell types of the human body and are amenable to genetic correction. This allows usage of iPSCs in the development of modern therapies for many virtually incurable human diseases. The review summarizes progress in iPSC research in the context of application in the cardiovascular field including modeling cardiovascular disease, drug study, tissue engineering, and perspectives for personalized cardiovascular medicine.

Details

Language :
English
ISSN :
25198521 and 25202588
Volume :
14
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Regulatory Mechanisms in Biosystems
Publication Type :
Academic Journal
Accession number :
edsdoj.5c84f31a00244fbeb4c80336b47d0c52
Document Type :
article
Full Text :
https://doi.org/10.15421/10.15421/022366