Back to Search
Start Over
Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus
- Source :
- mBio, Vol 12, Iss 2 (2021)
- Publication Year :
- 2021
- Publisher :
- American Society for Microbiology, 2021.
-
Abstract
- Acute antiviral functions of all nucleated cells rely on type I interferon (IFN-I) pathways triggered upon viral infection. Host responses encompass the sensing of incoming viruses, the activation of specific transcription factors that induce the transcription of IFN-I genes, the secretion of different IFN-I types and their recognition by the heterodimeric IFN-α/β receptor, the subsequent activation of JAK/STAT signaling pathways, and, finally, the transcription of many IFN-stimulated genes (ISGs).
- Subjects :
- Microbiology
QR1-502
Subjects
Details
- Language :
- English
- ISSN :
- 21507511
- Volume :
- 12
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- mBio
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5df41ff7727d458eb1c5cf6678139f31
- Document Type :
- article
- Full Text :
- https://doi.org/10.1128/mBio.03440-20