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Does perioperative oxandrolone improve nutritional status in patients with cachexia related to head and neck carcinoma?
- Source :
- Laryngoscope Investigative Otolaryngology, Vol 4, Iss 3, Pp 314-318 (2019)
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- Background Cancer cachexia affects up to over 50% of advanced head and neck cancer (HNC) patients. To date, the potential utility of anabolic steroids in perioperative cachectic HNC patients has not been determined. Methods Retrospective review of pre‐ and post‐oxandrolone administration prealbumin levels in 18 perioperative HNC patients between October 2007 and October 2014 at a tertiary academic medical center. Results The median pretreatment prealbumin was 88.5 mg/L. The median post‐treatment prealbumin was 227 mg/L. The median interval improvement of the prealbumin level was 131.5 mg/L. The median differences between the pretreatment and post‐treatment prealbumin levels were found to be statistically significant (P
Details
- Language :
- English
- ISSN :
- 23788038
- Volume :
- 4
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Laryngoscope Investigative Otolaryngology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5eedb6a79b0440049a8e72e09b8d122d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1002/lio2.268