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Rare variant contribution to cholestatic liver disease in a South Asian population in the United Kingdom
- Source :
- Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
- Publication Year :
- 2023
- Publisher :
- Nature Portfolio, 2023.
-
Abstract
- Abstract This study assessed the contribution of five genes previously known to be involved in cholestatic liver disease in British Bangladeshi and Pakistani people. Five genes (ABCB4, ABCB11, ATP8B1, NR1H4, TJP2) were interrogated by exome sequencing data of 5236 volunteers. Included were non-synonymous or loss of function (LoF) variants with a minor allele frequency
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Scientific Reports
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5f99e23ac98e467ea4d0f83ceaecfa77
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41598-023-33391-w