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Classical Hodgkin’s Lymphoma Presenting as Acute Hepatic Failure—One Case Report

Authors :
Sekhar Mukherjee
Shivesh Shanker Sahai
Pradipta Guha
Sanjoy Kumar Chatterjee
Source :
Cancer Biology & Medicine, Vol 7, Iss 6, Pp 373-376 (2010)
Publication Year :
2010
Publisher :
China Anti-Cancer Association, 2010.

Abstract

A 20-year-old boy presenting daily febrile episodes was suspected to have developed acute hepatic failure. Serologic tests ruled out infectious and autoimmune causes apart from drug toxicity. During clinical examinations, he was found to have generalized enlarged lymph nodes that were then taken biopsy. It was diagnosed as classical Hodgkin’s lymphoma based on histological examination of the lymph node. A bone marrow biopsy showed marrow infi ltration by Hodgkin’s lymphoma with hemophagocytosis and secondary myelofibrosis. A percutaneous liver biopsy demonstrated hepatic involvement of the same disease. After an extensive work-up, the cause of liver failure was figure out to be only attributed to the involvement of the lymphoma. Hodgkin’s lymphoma as a cause of hepatic failure is rare and young patients diagnosed as Hodgkin’s lymphoma causing hepatic failure has been reported very rarely so far.

Details

Language :
English
ISSN :
20953941
Volume :
7
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Cancer Biology & Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.60099b4529bb4ea09ea91dec5344b43e
Document Type :
article
Full Text :
https://doi.org/10.1007/s11805-010-0548-3