The Effects Of The Use Of A High-Efficiency, High-Flux Dialysis Membrane On The Nutritional Status Of Patients Receiving Maintenance Hemodialysis

It is possible to observe improvement in the general state of patients receiving maintenance hemodialysis, including decreased joint symptoms, decreased pruritus, and better appetite, by using a high-efficiency, high-flux dialysis membrane. We aimed to determine the effects of the use of a high-flux dialysis membrane on improvement in the nutritional status of dialysis patients. Two months before the replacement with a high-efficiency, high-flux dialysis membrane and one, three, six, and twelve months after the replacement, the subjective global assessment (SGA), biochemical markers, and a Body Composition Analyzer was used to assess the nutritional status and determine hemodialysis adequacy, along with a biochemical test, in 25 stable patients (M: F=10:15, 54.5±12.7 (37∼80) yrs). Of all the patients, 3 got better results from SGA, 12 the same results, and 10 worse results, in the follow-up period. There was no significant increase or decrease after the replacement with a high-flux dialysis membrane in biochemical parameters and nutritional parameters. While there was also no improvement in body weight, fat mass, muscle mass, lean fat mass, visceral fat, or the degree of edema measured by the body composition analyzer after the replacement, basal metabolism was improved from 1179.2±143.5 kcal before the replacement to 1264.8±145.4, 1241±138.3, and 1201.0±317.0 kcal one, three, twelve months after the replacement, respectively, on the average (p