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A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive

Authors :
K.C.S. Pontes
A.P.B. Borges
R.B. Eleotério
A.C.N. Frazão
D.P.D. Machado
E.C.C. Reis
R.V. Sepúlveda
T.S. Duarte
J.L. Laus
Source :
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Vol 66, Iss 3, Pp 655-664 (2014)
Publication Year :
2014
Publisher :
Universidade Federal de Minas Gerais, 2014.

Abstract

The objectives of this study were to compare surgical techniques and the effects of using n-butyl 2-cyanoacrylate and bovine amniotic membrane to repair perforated lesions in corneas. Penetrating keratoplasty was performed in sixty New Zealand White rabbits under general anesthesia. Group 1 (G1) was treated with n-butyl 2-cyanoacrylate, group 2 (G2) received a fragment of amniotic membrane through the anterior chamber and application of n-butyl 2-cyanoacrylate over the lesion, group 3 (G3) was treated with the same technique as G2 with the addition of an amniotic membrane bandage covering the cornea and sutured in the limbus region, and group 4 (G4) was treated with an amniotic membrane sutured to the lesion and an amniotic membrane bandage sutured in the limbus region. Clinical, histological and histomorphometric examinations of the corneas were performed. The membrane acted as a barrier for aqueous humor in G2 and G3, thereby keeping the surface dry for adhesive application; it also prevented the adhesive from contacting intraocular structures. The groups treated with amniotic membrane and surgical adhesive showed better results than the groups treated with either material alone. Thus, the combination of the membrane with the adhesive is recommended for this type of lesion.

Details

Language :
English, Portuguese
ISSN :
16784162
Volume :
66
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Publication Type :
Academic Journal
Accession number :
edsdoj.607ff705cc484b808f4789c1bf936b2b
Document Type :
article
Full Text :
https://doi.org/10.1590/1678-41625707