Synergistic Moderating Effects of L-Theanine and EGCG for the Prevention of Obesity and Hypercholesterolemia

Based on the high-fat diet of successfully modeled obese and hypercholesterolemic rats, using simvastatin as a positive control，the results of epigallocatechin gallate (EGCG, 83.3 mg·kg−1·d−1) + L-Theanine (16.7 mg·kg−1·d−1), EGCG (100 mg·kg−1·d−1) and L-theanine (100 mg·kg−1·d−1) continuously fed by gavage to high-fat diet SPF-grade SD rats for 56 d were compared to investigate the synergistic moderating effects of L-theanine and EGCG for the prevention of obesity and hypercholesterolemia. The results showed that compared with the normal group, there were significant differences (P