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In vitro Antibacterial and Antifungal Activities of Sorindeia madagascariensis and Albizia harveyi Stem Barks

Authors :
Paul Malaba Makoye
Sunday Mrutu
Innocent John Daniel
Mourice Nyangabo Mbunde
Joseph Sempombe
Veronica Mugoyela
Source :
Pharmaceutical Sciences and Research, Vol 9, Iss 1, Pp 51-58 (2022)
Publication Year :
2022
Publisher :
Universitas Indonesia, 2022.

Abstract

The emerging multi-drug-resistant pathogens urge continuous searches for new antimicrobial agents. This study investigated the in vitro antibacterial and antifungal activities of the stem barks of two plants, Sorindeia madagascariensis and Albizia harveyi. Broth microdilution assay was used to determine the minimum inhibitory concentrations (MICs) of hydroethanolic extracts of the stem barks against selected bacteria and fungi. Both plant extracts exhibited activity against all tested microorganisms and their minimum inhibitory concentrations (MICs) against bacteria and fungi were from 1.67 to 5.00 mg/mL and from 1.67 to 10.00 mg/mL, respectively. This study reports the antibacterial and antifungal activities of the hydroethanolic extracts of the stem barks of both plants. Antifungal activity of A. harveyi is being reported for the first time. We therefore suggest further investigation of bioactive compounds from stem barks of A. harveyi and S. madagascariensis with antibacterial and antifungal activities.

Details

Language :
English
ISSN :
24072354 and 24770612
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Pharmaceutical Sciences and Research
Publication Type :
Academic Journal
Accession number :
edsdoj.626ef45f13941debab4ff0bca9e4ced
Document Type :
article
Full Text :
https://doi.org/10.7454/psr.v9i1.1254