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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment
- Source :
- Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- Patient-derived xenograft models (PDX) have been extensively used to study the molecular and clinical features of cancers. Here the authors present a cohort of 536 PDX models from 25 cancers, as well as their genomic and evolutionary profiles and their suitability for clinical trials.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.6286532f9bc487a87943a142621d7a3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-021-25177-3