Role of molecular adsorbent recirculating system in methotrexate-induced acute liver failure: a case report and literature review

Authors :: T. Corbisier
André O. Von Bueren
W.B. Breunis
S. Grazioli
Source :: Frontiers in Pediatrics, Vol 12 (2024)
Publication Year :: 2024
Publisher :: Frontiers Media S.A., 2024.
Abstract: We describe the case of a 14-year-old girl with osteosarcoma who was treated with high-dose methotrexate (12 g/m2). Twenty-four hours after the infusion, her plasma methotrexate concentration was elevated at 937 μmol/L (normal

Subjects :: methotrexate toxicity
acute liver failure
acute kidney injury
extracorporeal treatment
case report
Pediatrics
RJ1-570

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