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An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.

Authors :
Kiran Shahane
Madhuri Kshirsagar
Srushti Tambe
Divya Jain
Srutee Rout
Maria Karolina Martins Ferreira
Suraj Mali
Purnima Amin
Prem Prakash Srivastav
Jorddy Cruz
Rafael Rodrigues Lima
Source :
Pharmaceuticals, Vol 16, Iss 4, p 611 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Calendula officinalis Linn. (CO) is a popular medicinal plant from the plant kingdom’s Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical constituents confer multifaceted biological effects such as anti-inflammatory, anti-cancer, antihelminthic, antidiabetes, wound healing, hepatoprotective, and antioxidant activities. Additionally, it is employed in cases of certain burns and gastrointestinal, gynecological, ocular, and skin conditions. In this review, we have discussed recent research from the last five years on the therapeutic applications of CO and emphasized its myriad capabilities as a traditional medicine. We have also elucidated CO’s molecular mechanisms and recent clinical studies. Overall, this review intends to summarize, fill in the gaps in the existing research, and provide a wealth of possibilities for researchers working to validate traditional claims and advance the safe and effective use of CO in treating various ailments.

Details

Language :
English
ISSN :
14248247
Volume :
16
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Pharmaceuticals
Publication Type :
Academic Journal
Accession number :
edsdoj.6449a477937341c6a60510a366f7a200
Document Type :
article
Full Text :
https://doi.org/10.3390/ph16040611