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Decreased serum levels of sex steroids associated with osteoporosis in a group of Romanian male patients
- Source :
- Romanian Journal of Laboratory Medicine, Vol 24, Iss 1, Pp 75-82 (2016)
- Publication Year :
- 2016
- Publisher :
- Sciendo, 2016.
-
Abstract
- Introduction. With age, sex hormone deficiency leads to reduced bone mineral density (BMD) in men. The aim of our research is to analyze the role of serum sex steroids in assessing BMD in the men included in this study. Materials and methods. This cross-sectional study included 146 men aged 65-85 years old with osteopenia or osteoporosis (study group) and 121 men with normal BMD (control group). Serum levels of total testosterone (Tt) and free testosterone (Tf) were measured by immunoassay, and estradiol (E2) levels were measured by the immunoenzymatic method. Femoral neck and lumbar spine BMD was examined by dual-energy X-ray absorptiometry. Results. Tf and E2 deficiency was significantly associated with low BMD (p=0.007). No association was found between Tt deficiency and reduced BMD. Tf levels (p
- Subjects :
- sex steroids
bone mineral density
men
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 22845623
- Volume :
- 24
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Romanian Journal of Laboratory Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.65548a2c18da407083e63a4b81c578f6
- Document Type :
- article
- Full Text :
- https://doi.org/10.1515/rrlm-2016-0014