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Short- and Long-Term Outcomes of Patients with Postoperative Arrhythmia after Liver Surgery

Authors :
Felix Rühlmann
Deborah Engelhardt
Alma Franziska Mackert
Mara Sophie Hedicke
Tobias Tichelbäcker
Andreas Leha
Markus Bernhardt
Michael Ghadimi
Thorsten Perl
Azadeh Azizian
Jochen Gaedcke
Source :
Biomedicines, Vol 12, Iss 2, p 271 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

Background: New-onset postoperative arrhythmia (PA) has previously been described as a pivotal risk factor for postoperative morbidity and mortality after visceral surgery. However, there is a lack of data concerning liver surgery. The incidence and impact of new-onset postoperative arrhythmia after liver surgery was, therefore, analyzed in a monocentric study. Methods: In total, n = 460 patients (221 female, 239 male) who underwent liver surgery between January 2012 and April 2020 without any prior arrhythmia in their medical history were included in this retrospective analysis. Clinical monitoring started with the induction of anesthesia and was terminated with discharge from the intensive care unit (ICU) or intermediate care unit (IMC). Follow-up included documentation of complications during the hospital stay, as well as long-term survival analysis. Results: Postoperative arrhythmia after liver surgery was observed in 25 patients, corresponding to an incidence of 5.4%. The occurrence of arrhythmia was significantly associated with intraoperative complications (p < 0.05), liver fibrosis/cirrhosis (p < 0.05), bile fistula/bile leakage/bilioma (p < 0.05), and organ failure (p < 0.01). Survival analysis showed a significantly poorer overall survival of patients who developed postoperative arrhythmia after liver surgery (p < 0.001). Conclusions: New-onset postoperative arrhythmia after liver surgery has an incidence of only 5.4% but is significantly associated with higher postoperative morbidity and poorer overall survival.

Details

Language :
English
ISSN :
22279059
Volume :
12
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Biomedicines
Publication Type :
Academic Journal
Accession number :
edsdoj.66c3c3a5b34c46a89ed7759fad94c39c
Document Type :
article
Full Text :
https://doi.org/10.3390/biomedicines12020271