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Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant Enterobacterales in the United States

Authors :
Victor I. Band
Sarah W. Satola
Richard D. Smith
David A. Hufnagel
Chris Bower
Andrew B. Conley
Lavanya Rishishwar
Suzanne E. Dale
Dwight J. Hardy
Roberto L. Vargas
Ghinwa Dumyati
Marion A. Kainer
Erin C. Phipps
Rebecca Pierce
Lucy E. Wilson
Matthew Sorensen
Erik Nilsson
I. King Jordan
Eileen M. Burd
Monica M. Farley
Jesse T. Jacob
Robert K. Ernst
David S. Weiss
Source :
mBio, Vol 12, Iss 1 (2021)
Publication Year :
2021
Publisher :
American Society for Microbiology, 2021.

Abstract

Heteroresistance is an underappreciated phenomenon that may be the cause of some unexplained antibiotic treatment failures. Misclassification of heteroresistant isolates as susceptible may lead to inappropriate therapy.

Subjects

Subjects :
Microbiology
QR1-502

Details

Language :
English
ISSN :
21612129 and 21507511
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
mBio
Publication Type :
Academic Journal
Accession number :
edsdoj.66ed1c01ff83414ba325c4ef742f6f0e
Document Type :
article
Full Text :
https://doi.org/10.1128/mBio.02881-20