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Pathogenic bacteria and treatment resistance in older cardiovascular disease patients with lung infection and risk prediction model

Authors :
Liu Hongbo
Xie Liyan
Xing Cong
Source :
Open Life Sciences, Vol 18, Iss 1, Pp 753-60 (2023)
Publication Year :
2023
Publisher :
De Gruyter, 2023.

Abstract

This study analyzes the distribution of pathogenic bacteria and their antimicrobial susceptibilities in elderly patients with cardiovascular diseases to identify risk factors for pulmonary infections. A risk prediction model is established, aiming to serve as a clinical tool for early prevention and management of pulmonary infections in this vulnerable population. A total of 600 patients were categorized into infected and uninfected groups. Independent risk factors such as older age, diabetes history, hypoproteinemia, invasive procedures, high cardiac function grade, and a hospital stay of ≥10 days were identified through logistic regression. A predictive model was constructed, with a Hosmer–Lemeshow goodness of fit (P = 0.236) and an area under the receiver operating characteristic curve of 0.795, demonstrating good discriminative ability. The model had 63.40% sensitivity and 82.80% specificity, with a cut-off value of 0.13. Our findings indicate that the risk score model is valid for identifying high-risk groups for pulmonary infection among elderly cardiovascular patients. The study contributes to the early prevention and control of pulmonary infections, potentially reducing infection rates in this vulnerable population.

Details

Language :
English
ISSN :
23915412
Volume :
18
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Open Life Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.686cbf4c4a7147ceb2175282c2f61789
Document Type :
article
Full Text :
https://doi.org/10.1515/biol-2022-0756