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Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting

Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting

Authors :
Benoit Rogez
Laeschkir Würthner
Anastasiia B. Petrova
Felix B. Zierhut
Dario Saczko-Brack
Maria-Ana Huergo
Christopher Batters
Erwin Frey
Claudia Veigel
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Curvature-mediating proteins are known to induce specific membrane shapes, but whether motorprotein-lipid interactions remodel membranes too remains unclear. Here authors show that curvature-dependent lipid interactions of myosin-VI remodel the membrane geometry into dynamic spatial patterns.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.69c820db8b4ae1b1ef6a2cc0804e10
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-11268-9