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Superenhancer–transcription factor regulatory network in malignant tumors

Authors :
Liang Yuan
Li Linlin
Xin Tian
Li Binru
Zhang Dalin
Source :
Open Medicine, Vol 16, Iss 1, Pp 1564-1582 (2021)
Publication Year :
2021
Publisher :
De Gruyter, 2021.

Abstract

This study aims to identify superenhancer (SE)–transcriptional factor (TF) regulatory network related to eight common malignant tumors based on ChIP-seq data modified by histone H3K27ac in the enhancer region of the SRA database.

Subjects

Subjects :
malignant tumors
super enhancers
transcription factors
chip-seq
rna-seq
core regulatory circuitry
superenhancer–transcription factor regulatory network
Medicine

Details

Language :
English
ISSN :
23915463
Volume :
16
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Open Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.6a46785b4db64d48bb07bc8d22b74050
Document Type :
article
Full Text :
https://doi.org/10.1515/med-2021-0326
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