Back to Search Start Over

Reproductive fitness and genetic risk of psychiatric disorders in the general population

Authors :
Niamh Mullins
Andrés Ingason
Heather Porter
Jack Euesden
Alexandra Gillett
Sigurgeir Ólafsson
Daniel F. Gudbjartsson
Cathryn M. Lewis
Engilbert Sigurdsson
Evald Saemundsen
Ólafur Ó Gudmundsson
Michael L. Frigge
Augustine Kong
Agnar Helgason
G. Bragi Walters
Omar Gustafsson
Hreinn Stefansson
Kari Stefansson
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Why genetic variants that confer risk for psychiatric disorders persist in the genome is an evolutionary conundrum. Here, Mullinset al. report association of polygenic risk for autism with having fewer children and polygenic risk for ADHD with higher reproductive fitness.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.6a60e54dd24e47ccb00660d46b48e9ad
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms15833