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Chronic Inflammatory Demyelinating Polyneuropathy after ChAdOx1 nCoV-19 Vaccination

Authors :
Caterina Francesca Bagella
Davide G. Corda
Pietro Zara
Antonio Emanuele Elia
Elisa Ruiu
Elia Sechi
Paolo Solla
Source :
Vaccines, Vol 9, Iss 12, p 1502 (2021)
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

Recently several patients, who developed Guillain–Barré syndrome characterized by prominent bifacial weakness after ChAdOx1 nCoV-19 vaccination, were described from different centers. We recently observed a patient who developed a similar syndrome, later in the follow up he showed worsening of the neuropathy two months after the initial presentation. Repeat EMG showed reduced nerve sensory and motor conduction velocities of both upper and lower limbs, and a diagnosis of chronic inflammatory demyelinating polyneuropathy (typical CIDP) was made according to established criteria. Our report expands on the possible outcomes in patients who develop Guillain–Barrè syndrome after COVID-19 vaccinations and suggest that close monitoring after the acute phase is needed in these patients to exclude a chronic evolution of the disease, which has important implications for long-term treatment.

Details

Language :
English
ISSN :
2076393X
Volume :
9
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Vaccines
Publication Type :
Academic Journal
Accession number :
edsdoj.6b35c73cd1f641689b59b45e54f552c6
Document Type :
article
Full Text :
https://doi.org/10.3390/vaccines9121502