Determination of fenamidone residues by surface-enhanced Raman spectroscopy

The purpose of this study is to establish a novel, simple and rapid surface-enhanced Raman spectroscopy (SERS) detection technology for fenamidone. Fenamidone is a fungicide widely used with curative activity against oomycete diseases. Gold nanoparticles (AuNPs) were prepared by improved trisodium citrate reduction method of chloroauric acid. As a surface-enhanced Raman scattering (SERS) active colloid, the optimized product had the advantages of high sensitivity, reproducibility and chemical stability. The Results showed that the detection limit of fenamidone adsorbed on AuNPs was 0.01 mg/kg. The linear response between SERS intensity and logarithmic concentration was R2 = 0.9562. The method was preliminary applied in tobacco sample and showed its potential to serve as an alternative rapid quantification method of fenamidone residues with simplicity, efficiency, high accuracy and precision.