Back to Search Start Over

Whole-Genome Sequencing of Drug-Resistant Mycobacterium tuberculosis Strains, Tunisia, 2012–2016

Authors :
Imen Bouzouita
Andrea Maurizio Cabibbe
Alberto Trovato
Henda Daroui
Asma Ghariani
Basma Midouni
Leila Essalah
Emna Mehiri
Daniela Maria Cirillo
Leila Slim Saidi
Source :
Emerging Infectious Diseases, Vol 25, Iss 3, Pp 547-550 (2019)
Publication Year :
2019
Publisher :
Centers for Disease Control and Prevention, 2019.

Abstract

To investigate transmission of drug-resistant strains of Mycobacterium tuberculosis in Tunisia, we performed whole-genome sequencing on 46 multidrug-resistant strains isolated during 2012–2016. Core-genome multilocus sequence typing grouped 30 strains (65.2%) into 3 clusters, indicating extensive recent transmission and Haarlem clone predominance. Whole-genome sequencing might help public health services undertake appropriate control actions.

Details

Language :
English
ISSN :
10806040 and 10806059
Volume :
25
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.6d7446dd584475b9f0b454b0c8e7102
Document Type :
article
Full Text :
https://doi.org/10.3201/eid2503.181370