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Harnessing copper-palladium alloy tetrapod nanoparticle-induced pro-survival autophagy for optimized photothermal therapy of drug-resistant cancer

Authors :
Yunjiao Zhang
Rui Sha
Lan Zhang
Wenbin Zhang
Peipei Jin
Weiguo Xu
Jianxun Ding
Jun Lin
Jing Qian
Guangyu Yao
Rui Zhang
Fanchen Luo
Jie Zeng
Jie Cao
Long-ping Wen
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

“Conventional chemotherapy-photothermal therapy combination has limited efficacy in drug resistant cancers. Here they develop Copper-palladium tetrapod nanoparticles to overcome these challenges and show them to work in synergy with autophagy inhibitors to treat drug resistant cancers”

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.6d9863f38f444e3b807155513160f3b2
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-06529-y