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Asymmetric cyanation of imines via dipeptide-derived organophosphine dual-reagent catalysis
- Source :
- Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
- Publication Year :
- 2016
- Publisher :
- Nature Portfolio, 2016.
-
Abstract
- The Strecker reaction is a power method for the synthesis of cyano-substituted compounds. Here the authors report a dual-reagent system for asymmetric Strecker reactions, where an in situformed organocatalyst/methyl acrylate zwitterionic adduct activates both the cyanide source and the electrophile.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.6f18c64ef0bd4553bc9b8c7431accbb9
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms12720