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COVID-19 Induced Acute Respiratory Distress Syndrome—A Multicenter Observational Study

Authors :
Johannes Herrmann
Elisabeth Hannah Adam
Quirin Notz
Philipp Helmer
Michael Sonntagbauer
Peter Ungemach-Papenberg
Andreas Sanns
York Zausig
Thorsten Steinfeldt
Iuliu Torje
Benedikt Schmid
Tobias Schlesinger
Caroline Rolfes
Christian Reyher
Markus Kredel
Jan Stumpner
Alexander Brack
Thomas Wurmb
Daniel Gill-Schuster
Peter Kranke
Dirk Weismann
Hartwig Klinker
Peter Heuschmann
Viktoria Rücker
Stefan Frantz
Georg Ertl
Ralf Michael Muellenbach
Haitham Mutlak
Patrick Meybohm
Kai Zacharowski
Christopher Lotz
Source :
Frontiers in Medicine, Vol 7 (2020)
Publication Year :
2020
Publisher :
Frontiers Media S.A., 2020.

Abstract

Background: Proportions of patients dying from the coronavirus disease-19 (COVID-19) vary between different countries. We report the characteristics; clinical course and outcome of patients requiring intensive care due to COVID-19 induced acute respiratory distress syndrome (ARDS).Methods: This is a retrospective, observational multicentre study in five German secondary or tertiary care hospitals. All patients consecutively admitted to the intensive care unit (ICU) in any of the participating hospitals between March 12 and May 4, 2020 with a COVID-19 induced ARDS were included.Results: A total of 106 ICU patients were treated for COVID-19 induced ARDS, whereas severe ARDS was present in the majority of cases. Survival of ICU treatment was 65.0%. Median duration of ICU treatment was 11 days; median duration of mechanical ventilation was 9 days. The majority of ICU treated patients (75.5%) did not receive any antiviral or anti-inflammatory therapies. Venovenous (vv) ECMO was utilized in 16.3%. ICU triage with population-level decision making was not necessary at any time. Univariate analysis associated older age, diabetes mellitus or a higher SOFA score on admission with non-survival during ICU stay.Conclusions: A high level of care adhering to standard ARDS treatments lead to a good outcome in critically ill COVID-19 patients.

Details

Language :
English
ISSN :
2296858X
Volume :
7
Database :
Directory of Open Access Journals
Journal :
Frontiers in Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.702ec5c7b4314286a02928e35a2a5b4a
Document Type :
article
Full Text :
https://doi.org/10.3389/fmed.2020.599533