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Epigenetic regulation of Neuregulin 1 promotes breast cancer progression associated to hyperglycemia

Authors :
Changhu Lee
Min Kim
Chanho Park
Woobeen Jo
Jeong Kon Seo
Sahee Kim
Jiyoung Oh
Chu-Sook Kim
Han Suk Ryu
Kyung-Hun Lee
Jiyoung Park
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Despite hyperglycemia has been associated to breast cancer, the underlying mechanisms are not completely understood. Here, the authors show that epigenetic regulation of Nrg1 gene during hyperglycemia promotes breast cancer development.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.70307856217b44f6a9332ad61e67b385
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-36179-8